Norepinephrine - Wikipedia
网页The noradrenergic neurons in the brain form a neurotransmitter system, that, when activated, exerts effects on large areas of the brain. The effects are manifested in alertness, arousal , and readiness for action.
Physiology, Noradrenergic Synapse - StatPearls - NCBI Bookshelf
网页2023年5月1日 · First identified in the 1940s by Swedish physiologist Ulf von Euler, norepinephrine, also known as noradrenaline, is a neurotransmitter of the brain that plays an essential role in the regulation of arousal, attention, cognitive function, and stress reactions. It also functions as a hormone peripherally as part …
The Neuromodulatory Role of the Noradrenergic and Cholinergic …
网页2022年7月7日 · Noradrenergic LC neurons possess long dendrites that pass through the surrounding small nuclei-like regions around the LC, which receive separate inputs from a variety of brain regions, including the prefrontal and infralimbic cortex, the amygdala, and the dorsal raphe nucleus .
role of noradrenaline in cognition and cognitive disorders | Brain ...
网页2021年3月16日 · Many aspects of cognition and behaviour are regulated by noradrenergic projections to the forebrain originating from the locus coeruleus, acting through alpha and beta adrenoreceptors. Loss of these projections is common in neurodegenerative diseases and contributes to their cognitive and behavioural deficits.
Locus coeruleus: a new look at the blue spot - Nature
网页2020年9月17日 · The locus coeruleus (LC), or ‘blue spot’, is a small nucleus located deep in the brainstem that provides the far-reaching noradrenergic neurotransmitter system of the...
Norepinephrine - SpringerLink
网页2022年9月13日 · Norepinephrine (NE) is a neurotransmitter of the brain that has a vital role in the modulation of cognition, arousal, attention, and stress responses. In the periphery, NE functions as a hormone as a part of the “fight or flight” response in …
Modular organization of the brainstem noradrenaline system
网页2017年9月18日 · Neurons in the brainstem LC are the major source of noradrenaline to the forebrain, through what was traditionally thought to comprise a homogeneous population of LC noradrenaline neurons...
Norepinephrine: A Neuromodulator That Boosts the Function of …
网页2012年6月21日 · Norepinephrine (NE) is a neuromodulator that in multiple ways regulates the activity of neuronal and non-neuronal cells. NE participates in the rapid modulation of cortical circuits and cellular energy metabolism, and on a slower time scale in neuroplasticity and inflammation.
The locus coeruleus and noradrenergic modulation of cognition
网页2009年2月4日 · The noradrenergic nucleus locus coeruleus (LC) is a tiny cluster of cells located bilaterally in the pons just under the fourth ventricle. Despite its small size (it groups just 1,500...
Brainstem noradrenergic neurons: Identifying a hub at the …
网页2022年9月15日 · Brainstem noradrenergic neurons form a node integrating many efferents projecting to distinct areas such as those regulating cognition and skeletal muscle structure and function and receive dissimilar afferents through established circuits to coordinate organismal responses to diverse challenges.
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