MicroRNA - an overview | ScienceDirect Topics
网页MicroRNAs are short RNA molecules of about 22 nucleotides that regulate gene expression by binding to mRNA, leading to silencing or degradation of the target mRNA. They play critical roles in various biological processes and are abundantly present in all human cells, controlling cellular functions like proliferation, differentiation, and apoptosis.
An overview of microRNAs: Biology, functions, therapeutics, and ...
网页MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in posttranscriptional regulation of gene expression. They are powerful regulators of various cellular activities including cell growth, differentiation, development, and apoptosis.
microRNAs in action: biogenesis, function and regulation
网页2023年6月28日 · miRNAs are RNAs ~22 nucleotides in length that derive from longer primary miRNA (pri-miRNA) transcripts, which bear one or more hairpins (Fig. 1a). Most miRNA hairpins derive from non-coding...
Overview of MicroRNA Biogenesis, Mechanisms of Actions, …
网页2018年8月3日 · MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA sequences into primary miRNAs and processed into precursor miRNAs, and …
MicroRNAs and their targets: recognition, regulation and an
网页2012年3月13日 · MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways. These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in repressed gene...
MicroRNA: Biogenesis, Function and Role in Cancer - PMC
网页MicroRNAs are small, highly conserved non-coding RNA molecules involved in the regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III, generating precursors that undergo a series of cleavage events to form mature microRNA.
MicroRNAs: understanding their role in gene expression and cancer
网页2021年7月8日 · MicroRNAs are small RNA molecules that regulate gene expression in cells. These small molecules comprise 17 to 25 nucleotides and are able to recognize target messenger RNAs by sequence complementarity and regulate their protein translation. Different microRNAs are expressed in all human cells.
MicroRNAs: small RNAs with a big role in gene regulation
网页2004年7月1日 · MicroRNAs are a family of small, non-coding RNAs that regulate gene expression in a sequence-specific manner. The two founding members of the microRNA family were originally identified in...
MicroRNAs: genomics, biogenesis, mechanism, and function
网页2004年1月23日 · MicroRNAs (miRNAs) are endogenous approximately 22 nt RNAs that can play important regulatory roles in animals and plants by targeting mRNAs for cleavage or translational repression.
Overview of MicroRNA Biogenesis, Mechanisms of Actions, …
网页2018年8月3日 · MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA sequences into primary miRNAs and processed into precursor miRNAs, and …
- 某些结果已被删除