Competitive androgen receptor antagonists are used to treat prostate cancer but, even in the presence of such drugs, overexpression of androgen receptors can drive cellular proliferation ...
The University of California and the US Department of Veterans Affairs have patented androgen receptor (AR) antagonists reported to be useful for the treatment of prostate cancer.
The investigational drug BMS-986365 may help patients with mCRPC previously treated with ARPIs overcome drug resistance, despite their genomic status. The investigational dual androgen receptor ...
Androgen receptor antagonists showed agonistic activity in cells with increased androgen receptor levels; this antagonist-agonist conversion was associated with alterations in the recruitment of ...
The muscle that is contracting is called the agonist and the muscle that is relaxing or lengthening is called the antagonist. Key fact One way to remember which muscle is the agonist – it's the ...
In the last few years, large Phase III trials showed improvements in survival and outcomes and led to the approval of a CYP17 inhibitor (abiraterone), an androgen receptor antagonist (enzalutamide ...
South Indian star Suriya is reportedly cast as the antagonist in 'Dhoom 4', following actors like John Abraham, Hrithik Roshan, and Aamir Khan. Known for his villainous role as Rolex in 'Vikram ...