让人意外的发现是,IgG1-G396R变异体在全球人口中出现显著两极化分布态势,其在非洲、欧洲、美洲(含北美洲,中美洲和南美洲)和大洋洲的主体人口中出现频率极低(minor allele frequency,MAF,仅为万分之几),但是在如下族群人口中频率较高:Bougainville population ...
The developed statistical method paves the way for next generation demographic and selection inference by combining information from several heritable genomic and epigenomic markers.
Using NGS in prognostic assessments enhances myelofibrosis prognosis and survival estimates, representing a step toward personalized medicine in myelofibrosis.