For human xenograft experiments in mice and administration of primary human material not suspected of harboring a human pathogen, standard ARP handling practices for housing and cage changing can be ...

Overexpression of 4EBP1 in BT474 cells did not affect overall protein synthesis under normoxic conditions, but reduced it under hypoxic conditions (0.5% O 2). However, 4EBP1 overexpression ...

Nemati and colleagues assessed whether the genes involved in response to topotecan-based chemotherapy in a panel of human SCLC xenografts could be useful for guiding future clinical assessment.

The primary focus Patient-Derived Xenograft (PDX) Core is to develop, and provide to the Baylor PDX community, computational and bioinformatics infrastructure to support large scale generation, ...