This article from Molecular Devices explores how cell painting can be used in a 3D breast cancer spheroid model for ...

Different cell types have varying survival times. For example, in humans, white blood cells die between 60 and 86 hours after ...

A new proof-of-concept method reliably engineered a hotspot mutation of SF3B1, a gene-splicing gene, into diverse cancer cell lines, outperforming other contemporary editing approaches. Oncogenesis ...

Scientists from the Medical Faculty Mannheim, Heidelberg University have developed a model system that can be used to test ...

This means that immunotherapy treatments which rely on unleashing an influx of immune cells into the tumor will not work. This is a type of treatment resistance known as "immune escape." "As ...

A machine-learning method predicts whether a genetic variant is pathogenic and affects certain human tissues. The ...

Macrophages are important cellular reservoirs of chikungunya virus (CHIKV), but the viral and host determinants that ...