The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

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Researchers demonstrated that several findings in Alzheimer's disease are observed across disorders, identifying potential ...

For example, histone acetyltransferase (HAT) complexes are thought to activate gene expression by modifying chromatin-associated ... function of cancer stem cell marker and hSAGA subunit USP22 ...

One way to tell is to ask about your "markers." When you're being treated for osteoporosis, your doctor orders a blood or urine test. This reveals several markers -- levels of different enzymes ...

His research interests in proteomics include the discovery of normal and disease markers using targeted quantitative mass spectrometry ... and RNA-binding proteins and revealed important paradigms of ...

Malod-Dognin, N Pancaldi, V Valencia, A and Pržulj, N 2020. Chromatin network markers of leukemia. Bioinformatics, Vol. 36, Issue. Supplement_1, p. i455. Gumbsch ...

Context-dependent chromatin accessibility determines the developmental or fibrogenic nature of ... The cell adhesion molecule L1CAM is a marker of the metastasis initiating phenotype in breast, lung, ...

Human papillomavirus (HPV) and hyperactivated YAP1 form a YAP1-HPV oncogenic alliance to drive the malignant transformation ...

With respect to laboratory testing, an elevation in levels of the serum marker CA 19-9 has been associated with an increased risk of malignant transformation. 51,52 Similarly, new-onset diabetes ...