We study all of the protein components of chromatin with an emphasis on understanding how multiple sources of variation function in concert or combination with each other. A major, but not exclusive ...
Kumamoto University researchers have made a discovery that sheds light on how the HMGA2 gene—an essential transcriptional activator involved in chromatin modification—regulates stress ...
Dr Radzisheuskaya’s group investigates how post-translational modifications on histone proteins regulate genome organization and stability and how they contribute to the development of cancer. Alex is ...
DNA damage repair and transcription both require large reorganizations of nucleosomes and chromatin structures by histone modifications and chromatin remodelers, which are tightly controlled by a ...
In a study published in Tree Physiology on June 21, 2024, Assistant Professor Takanori Saito and his colleagues explore the epigenetic modifications in chromatin structures and transcriptional ...