For a general summary overview, the major branching pathways that lead from arachidonic acid to the eicosanoids are shown in Figure 5. Note that the COX enzymes are positioned under one major ...

This theory holds that cytokines, rather than other non-protein-type mediators of inflammation such as eicosanoids, orchestrate the multicellular conspiracy among immunocytes such as dendritic ...

This review highlights the potential of lipidomic and metabolomic biomarkers in predicting breast cancer prognosis and ...

High maternal linoleic acid intake during pregnancy may impact fetal development and increase the risk of obesity and ...

“Healthy fats include unsaturated fats such as those found in olive oil, avocado and certain nuts and polyunsaturated fats ...

They also help produce hormones that regulate inflammation and immune function, including eicosanoids. Engaging in physical activity stimulates the production of endorphins, often referred to as the ...

eicosanoids, leukotrienes, cytokines) involved in inflammation. The pharmacologic effects of beta 2-adrenoceptor agonist drugs, including vilanterol, are at least in part attributable to ...

eicosanoids, leukotrienes, and cytokines) involved in inflammation and in the asthmatic response. These anti-inflammatory actions of corticosteroids may contribute to their efficacy in asthma.

Although nicotine appears to be the beneficial ingredient, the precise mechanism of action remains unclear. As the cause of ulcerative colitis remains unknown there is much opportunity for ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The metabolism of LA leads to the synthesis of AA and pro-inflammatory eicosanoids (thromboxane prostaglandins and ...