Researchers at HSE University and the RAS Institute of Bioorganic Chemistry have discovered that a common method of studying ...

[Caption] Pre-mRNA are processed by the spliceosome to remove various exons or introns through ... often distinguishing between cell types more accurately than gene expression. 1 During development, ...

RNA-sequencing has become a cornerstone in the study of gene expression, offering insights beyond mere mRNA transcript ...

Scientists from Spirovant Sciences describe SP-101, a novel adeno-associated virus (AAV) gene therapy for the treatment of ...

Scientists from Spirovant Sciences describe SP-101, a novel adeno-associated virus (AAV) gene therapy for the treatment of cystic fibrosis (CF) in the peer-reviewed journal Human Gene Therapy.

Treatment with OTX-2002 led to controlled downregulation of MYC gene expression and resulted in significant inhibition of tumor growth as a ...

Investigators suggest that further research could help discover potential therapeutic approaches that leverage the alternative splicing-nonsense-mediated decay process.

Structural studies reveal the mechanism by which the mRNA nuclear export machinery engages with nascent transcripts through interaction with the cap binding complex.

Scientists from Spirovant Sciences describe SP-101, a novel adeno-associated virus (AAV) gene therapy for the treatment of ...

[18] The integration of the provirus always occurs co-linearly with the expression unit LTR–genes ... genome is transcribed and the resulting mRNA is polyadenylated by signals located in ...