University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system. The discovery ...

Ongoing research investigating how HIV remains as a latent reservoir in resting T helper cells to ensure viral persistence in patients that have undergone treatment with highly active antiretroviral ...

But latent reservoirs are composed of more than just T-cells; in fact, they contain dozens of diverse cell types, each with ...

HIV infects and attacks immune-system cells, using their own machinery to make copies of itself. Even with effective treatment, some go into a resting, or latent, state - so they still contain the ...

In this small study, adding valproic acid to intensified antiretroviral therapy significantly depleted HIV in resting CD4 cells in vivo. Similar, although less dramatic, reductions of the latent ...

Identifying latent and asymptomatic tuberculosis infection in HIV-positive patients is important ... median CD4 count at test was 458 cells/μl. A negative test was found in 452 samples and ...

By targeting infected cells in the brain ... new study shows virus-like particle can effectively 'shock and kill' latent HIV reservoir in those living with chronic ... Researchers Open New ...

Dr. Shen has ongoing research studying latent reservoirs of HIV infection. She is investigating the mechanisms of how the reservoirs are formed and potential ways to remove the latent reservoir. Her ...

Some of them are being studied and, in some cases, used in clinical trials, to defend humans against HIV infection, treat HIV infection, and kill HIV-infected CD4+ T cells in latent reservoirs. A ...

Our mission is to provide a state-of-the-art facility, expertise, and education in advanced quantitative light microscopy to support Drexel University’s research community The Cell Imaging Center (CIC ...