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Smithsonian Magazine
1 天
In Case Humans Go Extinct, This Memory Crystal Will Store Our Genome for Billions of Years
Scientists have created "a form of information immortality" meant to instruct future species on how to recreate humans. But ...
10 天
on MSN
Scientists expand the genetic alphabet to create new proteins
Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words. But ...
生物谷
3 天
Nature子刊:周英思/黄锦海/胥春龙/左二伟团队开发新型TadA碱基编辑器 ...
该研究通过简易的蛋白质改造策略,利用TadA同源物开发靶向范围更广的胞嘧啶碱基编辑器,并首次在DMD小鼠模型中实现了外显子55的跳跃。 碱基编辑(Base editing,BE)可以实现单个碱基的精准编辑,被认为是更安全的基因编辑方式,在基础研究、药物开发、基因 ...
8 天
Rewriting Biology’s Rules: Scientists Have Expanded the Genetic Alphabet To Create New ...
Scripps Research scientists have created a method using four-nucleotide codons to incorporate non-canonical amino acids into ...
生物谷
7 天
寿命延长40%!江南大学研究发现,这种植物+亚精胺,具有协同抗衰作用
研究显示,铁皮石斛多糖和亚精胺联合使用具有协同抗衰老作用,当铁皮石斛多糖浓度为250 mg/L和亚精胺29 mg/L时,延寿益处最大,可将秀丽隐杆线虫的寿命延长40%,协同作用可能主要通过改变脂质代谢途径来介导的,为抗衰老提供了一种新方向。
Scientific American
4 天
Reshaping Sickle Cell Treatment with Patient Perspectives
Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine ...
The American Journal of Managed Care
14 小时
New Research Unearths Evidence of Global Metabolic Disruption in Patients With SMA
A recent analysis investigated the state of metabolic disruption experienced by patients with spinal muscular atrophy (SMA), ...
GEN
8 天
Genetic Alphabet Expanded to Create New Proteins
The Scripps technique could be used to re-engineer existing proteins—or create entirely new ones—that have utility in a range ...
The EMBO Journal
8 天
Glutaminolysis provides nucleotides and amino acids to regulate osteoclast differentiation ...
Metabolic rewiring is essential for osteoclast differentiation and bone resorption. This study shows that glutaminolysis ...
15 天
从有毒气体到生命守护者,药理学家为一氧化氮正名
一氧化氮(NO)曾普遍被视为一种有毒有害气体,应尽可能远离。然而,后来的科学研究揭示它在生物体内发挥极为重要的生理作用,NO ...
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