achieving widespread and dense myelin basic protein (MBP) expression by 4 weeks after grafting. Adult OPCs generated oligodendrocytes more efficiently than fetal OPCs, and ensheathed more host ...

Oligodendrocytes, the myelinating cells of the central nervous system (CNS), play a crucial role in myelin generation, maintenance, and repair after CNS injuries and in demyelinating diseases.

How oligodendrocytes use fatty acid metabolism as an energy reserve to maintain axonal function and myelin stability when ...

We created OPC-specific conditional knockout mice and showed that C1QL1 deficiency reduces the differentiation of OPCs into oligodendrocytes and reduces myelin production during both development ...

Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

Prineas, John W. and Parratt, John D. E. 2012. Oligodendrocytes and the early multiple sclerosis lesion. Annals of Neurology, Vol. 72, Issue. 1, p. 18. Newville ...

In experiments conducted in mice, deleting the gene that codes for C1QL1 caused a delay in the rate at which oligodendrocytes (the cells that make myelin) mature, leading to reduced myelination of ...

To learn more about the lives of oligodendrocytes, Robert Hill, a neurobiologist at Dartmouth College and coauthor on the study, turned to cell death. While Hill and his team have studied ...

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