Scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (WPI-iCeMS) have uncovered new details about ...
近年来,RNA干扰(RNAi)技术在基因表达调控领域潜力巨大,逐渐成为治疗遗传性疾病和癌症等重大疾病的前沿技术。然而,RNA的递释效率及其安全性一直是其临床应用中的关键难题。虽然已有如N-乙酰半乳糖胺(GalNAc)和脂质纳米颗粒(LNP)等RNA递释系统在临床使用,但它们在细胞内溶酶体的逃逸效率仍然较低(仅为1-4%),限制了其疗效。
Scientists at Kyoto University have discovered how cells control phospholipid distribution in their membranes.
Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to ...
Scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (WPI-iCeMS) have uncovered new details about ...
How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from ...
Scientists have uncovered new details about how cells manage the distribution of lipids in their cell membrane. These lipids, known as phospholipids, are arranged in a bilayer of membranes, regulating ...
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have ...
New data presented today demonstrate that TROP2 expression as measured by quantitative continuous scoring (QCS), a ...
Cancer cells can use lipids not just as fuel, but as a means to obscure inflammatory signals, enabling immune evasion.