The retention of DNMT1 and its cofactor UHRF1 in the cytoplasm is considered a major reason for passive DNA demethylation in the oocyte and early embryonic development. However, the mechanisms by ...

Conclusion Epigenetic PPARγ suppression plays a key role in OA development and PPARγ preservation via promoter demethylation possesses promising therapeutic potentials in clinical treatment of OA and ...

Direct racemic separations without derivatization. Separate enantiomers of pharmaceuticals, such as hexobarbital, ibuprofen and profenamine, are complete with ULTRON ES-OVM. ULTRON ES-Pepsin ...

A large segment of the CYP2C19 rapid metabolizer subgroup is nonresponder to the PPI treatment, only partial symptom relief in GERD, more frequent unsuccessful eradication therapy and lower ...