As discussed already, misfolded proteins result when a protein follows the wrong folding pathway or energy-minimizing funnel, and misfolding can happen spontaneously. Most of the time, only the ...

Protein misfolding has become a hot topic in the biopharma industry, with a clutch of emerging companies targeting the broad range of diseases that feature aberrant proteins. Wren Therapeutics for ...

With protein misfolding and aggregation prevalent in neurodegeneration, cancer, metabolic and ophthalmic diseases, the unmet clinical need presents huge opportunity to accelerate the discovery and ...

One theory is that the oligomer serves as a storage depot for monomers, which do the real work of suppressing protein misfolding. It's an idea that the Joachimiak Lab will test in future studies.

ABOVE: Protein misfolding plays an important role in many neurodegenerative disorders. © istock.com, Eoneren. W hen Julie ...

Improved amplification tests can help detect chronic wasting disease (CWD) in the saliva, urine, and feces of white-tailed ...

A shared interest in the biology of aging brought a chemist, a geneticist and a biologist together to found Proteostasis Therapeutics. In 2006, chemist Jeffery Kelly from The Scripps Research ...

Analyst Jason McCarthy from Maxim Group reiterated a Buy rating on Gain Therapeutics (GANX – Research Report) and keeping the price ...

Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, ...

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.