Neurodegenerative diseases are characterized by the progressive death of neurons that cause neurological and neuropsychological symptoms, including Alzheimer's disease (AD), Parkinson's disease (PD), ...
Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
Protein misfolding diseases because of its impacts on human health and potential for transformative therapeutic intervention. Other interests include molecular biology and protein biochemistry.
Loss-of-function mutations affecting the cystic fibrosis transmembrane conductance regulator (CFTR) cause CF. Class II CFTR mutations including F508del (present in approximately 90% of patients with ...