▎药明康德内容团队编辑  在早期胚胎发育过程中，从最初的受精卵开始，一次次有丝分裂构成了不断生长的胚胎。而每一次分裂都伴随着DNA复制，以确保每个子代细胞都含有完整的遗传信息。当然，这是理想状态。实际情况是，在早期胚胎发育过程中，DNA复制时常出错、导致染色体分离异常，并且这种异常出现的频率明显高于体细胞 ...

DNA methylation, essential for regulating gene expression and cell function, is crucially maintained by CDCA7, which ...

Damage to non-coding DNA accumulates more in slowly proliferating tissues, contributing to different rates of aging across ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

This article is going to help the students to prepare for the exam. 1. Which of the following occurs as a result of DNA replication being semi-conservative? A)An AChromosome number becomes half in the ...

Published online on Aug. 10 in Nucleic Acids Research, the paper focuses on the DNA damage response pathway and demonstrates how this pathway can reduce the function of a viral enzyme, a helicase, ...

A new process, nucleophagy, repairs damaged DNA that is particularly relevant for patients undergoing colorectal cancer ...

Careful replication and segregation of the DNA molecule, packaged into chromosomes, allows for the accurate inheritance of genetic instructions to each new daughter cell. DNA replication is a ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication.

DNA methyltransferase 1 (DNMT1) is an important DNA methyltransferase that maintains DNA methylation. The retention of DNMT1 ...