Durable Clinical Benefit Observed Beyond a Year on Treatment in Heavily Pre-Treated PatientsBoston (September 16, 2024) — Allarity ...

CY-101 well tolerated with early signs of clinical activity, especially in tumors with dysregulated Wnt/β-catenin signalling CY-101 granted ...

(“Allarity” or the “Company”) (NASDAQ: ALLR), a clinical-stage pharmaceutical company dedicated to developing personalized ...

Here, we report that Wnt3a either induces O-GlcNAcylation rapidly via the Ca 2+-PKA-Gfat1 axis, or increases it in a Wnt-β-catenin-dependent manner following prolonged stimulation. Importantly, we ...

Overexpression of α1,2-fucosylated GSLs impairs SMAD activation despite BMP4 presence, suggesting α-fucosyl end groups as BMP ...

DiogenX, a biotech company focused on regenerating insulin-producing beta cells for the treatment of diabetes, today announces the appointment of Eleanor L. Ramos, MD, as an Independent Board ...

World Trade Center (WTC) exposure is associated with increased DNA methylation, which may contribute to breast cancer, according to a study published in the June issue of Environmental Epidemiology.

A new review was published in Oncotarget's Volume 15 on August 2, 2024, entitled, “Targeting WNT5B and WNT10B in osteosarcoma ...

WNT5B, a β-catenin-independent ligand, and WNT10B, a β-catenin-dependent WNT ligand, are each expressed ... whether the canonical or non-canonical pathways are activated, and this remains ...

Methods: We performed transcriptome sequencing of SKPs and CEC-like cells. Further, we focused on the possible enriching pathways, including PI3K/Akt, MAPK/Erk, WNT/β-catenin, and important ...