Trastuzumab - Wikipedia
网页Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. [20] [17] [21] [22] It is specifically used for cancer that is HER2 receptor positive. [20] It may be used by itself or together with other chemotherapy medication. [20]
Herceptin (Trastuzumab): Side Effects, How it Works, and More
网页Herceptin (trastuzumab) can be an effective treatment both before and after surgery for people with HER2-positive breast cancer. Learn more.
Trastuzumab - NCI - National Cancer Institute
网页Trastuzumab is approved to be used alone or with other drugs to treat: Breast cancer that is HER2 positive (HER2+). It is used in patients with: Hormone receptor-negative or high-risk cancer. It is given: As combination therapy with: Doxorubicin hydrochloride, cyclophosphamide, and either paclitaxel or docetaxel; or; Docetaxel and carboplatin.
Trastuzumab Uses, Side Effects & Warnings - Drugs.com
网页2024年3月26日 · What is trastuzumab? Trastuzumab is used to treat certain types of breast cancer or stomach cancer, sometimes in combination with other cancer medicines. trastuzumab is sometimes used when the cancer has spread to other parts of the body (metastatic). Trastuzumab may also be used for purposes not …
Trastuzumab - StatPearls - NCBI Bookshelf
网页2024年6月22日 · Trastuzumab is an FDA-approved antineoplastic biologic that targets HER2-positive breast and gastric cancer. This activity outlines trastuzumab's various indications and off-label uses, including its combination with anthracycline or taxane-based chemotherapy for breast cancer, as monotherapy or in …
Trastuzumab: Uses, Interactions, Mechanism of Action
网页Trastuzumab is a monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers.
曲妥珠单抗 - 维基百科，自由的百科全书
网页曲妥珠單抗 （通用名， 國際非專利藥品名稱： Trastuzumab，商品名： 赫賽汀 （中國大陸及港澳）、 賀癌平 （台灣），羅氏Roche藥廠生產）是一種作用於 人類表皮生長因子受體II 的 單株抗體，主要用於治療某些HER-2陽性乳癌。 作用機轉. 大約有20-30%的乳癌會有HER-2過度表現的現象。 HER-2是細胞膜上的一種接受器，與人類 表皮生長因子 EGF有高度專一性。 當EGF與HER-2結合後，會造成HER-2的 雙聚體化，進而引發 自體磷酸化 而傳遞 …
Trastuzumab Deruxtecan versus Trastuzumab Emtansine for …
网页2022年3月23日 · Trastuzumab deruxtecan (also known as T-DXd and DS-8201) is an antibody–drug conjugate consisting of a humanized anti-HER2 monoclonal antibody linked to a topoisomerase I inhibitor payload...
Trastuzumab — Mechanism of Action and Use in Clinical Practice
网页2007年7月5日 · One such medication is trastuzumab (Herceptin, Genentech), a humanized monoclonal antibody. Trastuzumab binds to the extracellular juxtamembrane domain of HER2 and inhibits the proliferation...
Trastuzumab (Intravenous Route) - Mayo Clinic
网页Trastuzumab injection is used to treat HER2-overexpressing new or metastatic (cancer that has spread) breast cancer. It can be used alone or with other cancer medicines (eg, carboplatin, cyclophosphamide, docetaxel, doxorubicin, paclitaxel).