Methoxsalen: Uses, Interactions, Mechanism of Action
网页Takeuchi H, Saoo K, Yokohira M, Ikeda M, Maeta H, Miyazaki M, Yamazaki H, Kamataki T, Imaida K: Pretreatment with 8-methoxypsoralen, a potent human CYP2A6 inhibitor, strongly inhibits lung tumorigenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in female A/J mice.
Methoxsalen - Wikipedia
网页Methoxsalen (or xanthotoxin) sold under the brand name Oxsoralen among others, is a medication used to treat psoriasis, eczema, vitiligo, and some cutaneous lymphomas in conjunction with exposing the skin to ultraviolet (UVA) light from lamps or sunlight.
8-Methoxypsoralen has Anti-inflammatory and Antioxidant …
网页2021年9月6日 · In this study, we aimed to explore the role and mechanism of 8-Methoxypsoralen (8-MOP) in the OA model both in vitro and in vivo. The rat chondrocytes were treated with IL-1β, and the proliferation, apoptosis, inflammatory reactions and oxidative stress responses were determined after treatment with different concentrations of …
8-MOP (Methoxsalen): Side Effects, Uses, Dosage, Interactions ... - RxList
网页2023年1月31日 · What Is 8-MOP? 8-MOP (methoxsalen) is a naturally occurring substance that is reactive to light used in combination with UVA light therapy to treat severe psoriasis. What Are Side Effects of 8-MOP? 8-MOP may cause serious side effects including: hives, difficulty breathing, swelling of your face, lips, tongue, or throat,
Psoralen - LiverTox - NCBI Bookshelf
网页2020年1月16日 · 8-methoxsalen and 5-methoxsalen are furocoumarins referred to collectively as psoralens that have photosensitizing activity and are used orally and topically in conjunction with ultraviolet irradiation for the therapy of psoriasis and vitiligo.
methoxsalen (Rx) - Medscape Drugs & Diseases
网页Medscape - Indication-specific dosing for 8MOP, Oxsoralen (methoxsalen), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and...
8-Methoxypsoralen has Anti-inflammatory and Antioxidant Roles …
网页2021年9月6日 · Our results revealed that 8-MOP evidently reduced IL-1β-mediated apoptosis and inhibition of proliferation, and mitigated the expression of inflammatory cytokines and oxidative stress factors in chondrocytes. Additionally, 8-MOP promoted phosphorylated level of AMPKα, enhanced SIRT1 expression and inhibited the phosphorylation of NF-κB.
Methoxsalen Uses, Side Effects & Warnings - Drugs.com
网页2023年8月7日 · What is methoxsalen? Methoxsalen works by enhancing the body's sensitivity to ultraviolet light A (UVA). Methoxsalen is used in combination with UVA light therapy to treat severe psoriasis.
Xanthotoxin (8‐methoxypsoralen): A review of its chemistry ...
网页Xanthotoxin (8-methoxypsoralen): A review of its chemistry, pharmacology, pharmacokinetics, and toxicity
Methoxypsoralen, 8 - SpringerLink
网页2024年1月1日 · Plants, particularly typical fruit and vegetable crops, naturally contain 8-methoxypsoralen and other psoralens. Synthetic variants of 8-methoxypsoralen and 5-methoxypsoralen (bergapten) are frequently used as medications in skin photochemotherapy, such as the treatment of psoriasis, vitiligo, and mycosis fungoides with longwave ultraviolet (UV ...