Circular RNA - Wikipedia
网页In molecular biology, circular RNA (or circRNA) is a type of single-stranded RNA which, unlike linear RNA, forms a covalently closed continuous loop. In circular RNA, the 3' and 5' ends normally present in an RNA molecule have been joined together.
The biogenesis, biology and characterization of circular RNAs
网页2019年8月8日 · Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by specific...
Circular RNAs: Characterization, cellular roles, and ...
网页2022年5月17日 · Liu and Chen review the growing toolbox to characterize circular RNA, the resulting emerging understanding of their biological roles, and how circular RNA are being utilized for biomedical applications.
Advances in Circular RNA and Its Applications - PMC
网页2022年5月27日 · Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional linear RNAs (which have 5' and 3' ends), has a closed-loop structure that is unaffected by RNA exonucleases.
Specific expression and functions of circular RNAs
网页2022年2月15日 · In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by their covalently closed circular structure, have become a new research paradigm in RNA biology.
Molecular mechanisms of circular RNA translation - Nature
网页2024年6月14日 · Circular RNAs (circRNAs) are covalently closed single-stranded RNAs without a 5′ cap structure and a 3′ poly (A) tail typically present in linear mRNAs of eukaryotic cells. CircRNAs are...
Circular RNA: metabolism, functions and interactions with ...
网页2020年12月14日 · Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules that are ubiquitous across species ranging from viruses to mammals. Important advances have been made in the biogenesis, regulation, localization, degradation and modification of circRNAs.