Thymoma and Thymic Carcinoma Treatment (PDQ®) - NCI
网页2024年5月23日 · Combined-modality treatment consisting of induction chemotherapy followed by surgery and radiation therapy should be considered for all patients with unresectable stage III thymoma. The optimal strategy for induction therapy, which optimizes resectability rates and ultimately survival, is not defined.
The Management of Thymoma: A Systematic Review and Practice Guideline
网页Cisplatin, doxorubicin, and cyclophosphamide plus thoracic radiation therapy for limited-stage unresectable thymoma: an intergroup trial
Clinical presentation and management of thymoma and thymic ... - UpToDate
网页2024年4月3日 · Thymic tumors are rare neoplasms that arise in the anterior mediastinum. The clinical presentation, diagnosis, staging, and management of thymoma and thymic carcinoma are reviewed here. The pathology of thymic carcinomas, the initial approach to patients with an anterior mediastinal mass, and the diagnosis and management of thymic ...
Thymoma - StatPearls - NCBI Bookshelf - National Center for ...
网页2023年7月17日 · Patients with the unresectable disease are those with extensive pleural and pericardial metastases, un-reconstructable great vessel, heart or tracheal involvement, or distant metastases. Such patients should receive systemic therapy (either radiotherapy alone or chemoradiotherapy).
Treatment of Advanced Thymoma and Thymic Carcinoma
网页However, for advanced stage thymoma (stages III and IV) and thymic carcinoma, multimodality therapy plays a key role in successful management of disease. Neoadjuvant chemotherapy is delivered to make unresectable tumors resectable, and to increase the chances of performing complete surgical excision of the tumor.
Chemoradiotherapy for unresectable cases of thymic epithelial …
网页2017年1月31日 · Because of the rarity of thymic epithelial tumors (TETs), there is no treatment for managing unresectable tumors that is supported by a high level of evidence. We present here the clinical outcomes of concurrent or sequential chemoradiotherapy for patients with unresectable TETs.
Surgical, Radiation, and Systemic Treatments of Patients With …
网页Evidence-based recommendations were developed to improve the management of patients with thymic epithelial tumors. The guideline includes recommendations for surgical, radiation, and systemic treatments for patients with thymoma, thymic carcinoma, and thymic NETs separated by stage of disease using the TNM staging system.
Thymoma: From Chemotherapy to Targeted Therapy
网页2012年5月17日 · In locally advanced thymic malignancies (i.e., unresectable Masaoka stage III and IVA disease at time of diagnosis), chemotherapy aims at making feasible subsequent R0 resection to achieve long-term survival. 1,6 Several chemotherapy regimens have been used in this setting, mostly consisting of doxorubicin- …
Thymoma: A Focus on Current Therapeutic Management
网页2009年1月1日 · In primary unresectable thymomas, multimodal strategy nowadays includes neoadjuvant chemotherapy, extensive surgery, adjuvant radiotherapy, and in some cases, adjuvant chemotherapy. The most popular chemotherapy regimens combine cisplatin, adriamycin, etoposide, cyclophophamide, or ifosfamide.
Thymoma Treatment & Management: Medical Therapy, Surgical ... - Medscape
网页2024年8月12日 · The authors suggested that aggressive multimodal treatment is effective and may be curative in locally advanced, unresectable, malignant thymomas. Octreotide (0.5 mg SC q8hr) alone or with...