Genome-edited powdery mildew resistance in wheat without …
网页2022年2月9日 · Tamlo-R32, an engineered wheat mutant allele of the Mildew resistance locus O (MLO) gene, confers resistance to powdery mildew, retains robust wheat growth, and can be transferred...
Knockdown of MLO genes reduces susceptibility to powdery mildew …
网页2016年4月20日 · Erysiphe necator is the causal agent of powdery mildew (PM), one of the most destructive diseases of grapevine. PM is controlled by sulfur-based and synthetic fungicides, which...
Highly effective mlo -based powdery mildew resistance in …
网页2023年10月1日 · In this study, we report on the generation of powdery mildew resistant wheat lines with a range of different mutations in the three homoeologous Mlo genes of hexaploid wheat. In 24 out of the 25 generated lines we observed a high level of resistance, with development of a few mildew pustules only in some of the lines.
Structure, evolution and functional inference on the Mildew Locus …
网页2015年12月29日 · The Mildew Locus O (MLO) gene family encodes for plant-specific proteins structurally related to metazoan G-protein coupled receptors (GPCRs), harbouring seven transmembrane domains and a calmodulin-binding domain that is likely implicated in the perception of calcium-dependent stimuli [1, 2].
CRISPR/Cas9-mediated mutagenesis of VvMLO3 results in …
网页2020年8月1日 · The grapevine genes VvMLO3, VvMLO4, and VvMLO17, orthologous to the AtMLO2, AtMLO6, and AtMLO12 genes, respectively 29, are reported to exhibit rapid induction upon powdery mildew infection ...
NLR- and mlo-Based Resistance Mechanisms against Powdery Mildew …
网页2023年12月29日 · Powdery mildew (PM) is one of the most common Cannabis sativa diseases. In spite of this, very few documented studies have characterized the resistance genes involved in PM defense mechanisms, or sources of natural genetic resistance in cannabis. The focus of the present work is on the two primary mechanisms for qualitative resistance against ...
mlo‐based powdery mildew resistance in hexaploid bread wheat …
网页2016年8月27日 · In barley, natural and induced loss-of-function mutations of the Mildew resistance locus o (Mlo) gene confer broad-spectrum resistance against most B. graminis f.sp. hordei (Bgh) isolates, an effect that has been shown to last in the field for more than 30 years (Jørgensen, 1992; Lyngkjær et al., 2000).
Genome-wide identification and evolutionary analysis of MLO gene …
网页2022年1月1日 · Mutants lacking wild-type MLO (Mildew resistance Locus O) proteins show broad-spectrum resistance to the powdery mildew fungus, and dysregulated cell death control, with spontaneous cell death in response to …
Genome-wide identification and analysis of the MLO gene family …
网页2021年6月1日 · Powdery mildew (PM) disease is one of the most serious threats to Momordica charantia. Specific mildew resistance locus O ( MLO) genes associated with PM susceptibility have been explored in some plant species for mlo- based PM resistance. However, MLO has not been surveyed globally for candidate susceptibility factors in M. charantia. In this ...
Diversifying the menu for crop powdery mildew resistance - Cell …
网页2022年3月3日 · Powdery mildew, a potentially severe crop disease, can be controlled by mlo mutations, which suppress fungal proliferation but typically also reduce yield. Li et al., 2022. demonstrate that productivity can be restored by overexpressing a host sugar transporter, thus offering a new option for economically and …
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