Procarbazine | C12H19N3O | CID 4915 - PubChem
网页Procarbazine is a benzamide obtained by formal condensation of the carboxy group of 4- [ (2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of …
Procarbazine - Wikipedia
网页Procarbazine is a chemotherapy medication used for the treatment of Hodgkin's lymphoma and brain cancers. [1] For Hodgkin's it is often used together with chlormethine, vincristine, and prednisone while for brain cancers such as glioblastoma multiforme it is used with lomustine and vincristine. [1] It is typically taken by mouth. [1]
Procarbazine | C12H19N3O - ChemSpider
网页ChemSpider record containing structure, synonyms, properties, vendors and database links for Procarbazine, 671-16-9, 211-582-2.
Procarbazine: Uses, Interactions, Mechanism of Action
网页Procarbazine is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells.
Procarbazine - an overview | ScienceDirect Topics
网页Procarbazine is a substituted hydrazine derivative with a chemical structure similar to that of the monoamine oxidase inhibitors (MAOIs). Accordingly, procarbazine exhibits weak MAOI effects. Procarbazine itself is inert and must undergo metabolic activation to generate cytotoxic reactants, the mode of action of which is not clear.
Procarbazine - an overview | ScienceDirect Topics
网页2007年10月15日 · Mechanistically, procarbazine is a unique agent with multiple mechanisms of action that is not cross-resistant with other alkylating agents. It inhibits the incorporation of small DNA precursors, as well as RNA and protein synthesis. Procarbazine can also directly damage DNA through a methylation reaction, whose precise mechanism is …
Procarbazine Structure - C12H19N3O - Over 100 million …
网页The 2D chemical structure image of procarbazine is also called skeletal formula, which is the standard notation for organic molecules. The carbon atoms in the chemical structure of procarbazine are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to be ...
Chemical structures of procarbazine (A) and morin (B).
网页Chemical structures of procarbazine (A) and morin (B). Source publication. The role of flavonoid antioxidant, morin in improving procarbazine-induced oxidative stress on testicular function in...
Figure 1, [Chemical Structure of Procarbazine]. - 15th Report on ...
网页Chemical Structure of Procarbazine. An official website of the United States government. Here's how you know. The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. ...
Procarbazine hydrochloride - DrugBank Online
网页Procarbazine. An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease. See full entry for Procarbazine. Accession Number.
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